Well, if at least the girls would be growing in bonus, then the incremental part of the game would be playable in "endgame". Resetting hits its practical limit somewhere in the 4 digits. You would need high 5 digits to notice a big difference - the equivalent of a x8 warp increase.
I am currently finishing Alice scene 9. And no sweat there. Thanks to the forerunners I even know that I have enough money for the last scene.