Originally Posted by
sanahtlig
I've been thinking about writing a Rank 4 Accessory Quest guide. But briefly, most teams will want to use Mordred to ensure debuffs land and for Black Propaganda. Having Gaia in reserve, if available, is extremely handy for dealing with the final boss's Raging Overdrive. You'll need at least one source of healing, and ideally you'll want DEF at -40% before Vine. -ATK to -30-40% without eidolons is important for most teams except Fire.
That assumes maxed neutral-element teams. For non-maxed teams with elemental advantage, it's really going to depend on ATK power and specific characters available. If you don't have enough offensive power to burn the boss during Rage, you're going to quickly run into trouble, particularly when something goes wrong like a character dying prematurely or a debuff missing.