Vine has made my Wind team more or less invincible against Thunder, and she's only LV30 and I don't even have Hastur's DEF down skill upgraded yet. Bosses die nearly as fast as against my Water team now (which has to hold back to avoid bad transitions anyway). With Mordred and Sniper Shot, I can typically take the boss down before I even take damage from the Rage Overdrive. Vine has made runs 50% less painful, and is a huge stress relief over running Cthulhu and having to worry about whether she'll even survive til the final boss.