This is just me but I won't ignore the defender weapons completely. You never know if gacha will troll you and drop you a bunch of weapons to push you to another phantom grid, only to find out that you're one weapon short.

Depending on play style, 30% defender is also actually not terrible if you have an otherwise glass cannon build like Ophiel lance grid or something.

This is extremely niche, but if you want to do infinite turtling for fire tower, you'll most likely want this seraph defender hammer especially if you missed Monoceros like I did.