Why are you making it harder for yourself? Max out inventory space ASAP, it's by far the best thing you can get with Jewels.
Once you've done that, inventory management is something you'll need to every day. At least until the Second Anniversary update (daily Gem Gacha draws drop from 1000 -> 160), which is still far away.I think you need more inventory space. It's not like you'll get whatever you want with Jewels anyway
Also, your question is rather silly. You obviously have more resources than what you can spend (right?), and yet you're still asking if it's smart to spend your resources or waste them.